2-Chloro-3-Pyridinyl Methanol
(2-Chloro-3-pyridinyl)methanol
CAS: 42330-59-6
Molecular Formula: C6H6ClNO
2-Chloro-3-Pyridinyl Methanol - Names and Identifiers
| Name | (2-Chloro-3-pyridinyl)methanol |
| Synonyms | 2-Chloro-3-Pyridinyl 2-Chloropyridine-3-Methanol 2-Chloro-3-pyridinemethanol 2-Chloro-3-(hydroxymethyl... 2-Chloro-3-Pyridinyl Methanol (2-CHLORO-3-PYRIDINYL)METHANOL (2-Chloro-3-pyridinyl)methanol (2-chloropyridin-3-yl)methanol (2-CHLORO-PYRIDIN-3-YL)-METHANOL 2-Choro-3-(hydroxymethyl)pyridine 2-Chloro-3-(hydroxymethyl)pyridine 2-CHLORO-3-(HYDROXYMETHYL)PYRIDINE |
| CAS | 42330-59-6 |
| InChI | InChI=1/C6H6ClNO/c7-6-5(4-9)2-1-3-8-6/h1-3,9H,4H2 |
| InChIKey | HMPDWSBKPCOQDW-UHFFFAOYSA-N |
2-Chloro-3-Pyridinyl Methanol - Physico-chemical Properties
| Molecular Formula | C6H6ClNO |
| Molar Mass | 143.57 |
| Density | 1.324±0.06 g/cm3(Predicted) |
| Melting Point | 54 °C |
| Boling Point | 112℃/0.2mm |
| Flash Point | 121.2°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.00227mmHg at 25°C |
| Appearance | Bright yellow needle |
| Color | White to Gray to Brown |
| pKa | 13.00±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.572 |
| MDL | MFCD01935961 |
2-Chloro-3-Pyridinyl Methanol - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN2811 |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
2-Chloro-3-Pyridinyl Methanol - Introduction
(2-Chloro-3-pyridinyl)methanol is an organic compound, the chemical formula is C6H6ClNO, and the structural formula is ClC6H4CH(OH)CH3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance:(2-Chloro-3-pyridinyl) The methanol is a colorless or light yellow solid.
-Melting point: about 78-80°C.
-Boiling point: about 267-269°C.
-Solubility: Soluble in most organic solvents, such as ethers and alcohols.
Use:
- (2-Chloro-3-pyridinyl)methanol can be used as an important reagent in organic synthesis.
-It is commonly used in the synthesis of other pyridine compounds, such as pesticides, glyphosate, etc.
Preparation Method:
-A common synthesis method is to obtain (2-Chloro-3-pyridinyl)methanol by reacting 2-pyridinyl with hydrogen chloride. Ferrous chloride (FeCl2) is used as a catalyst in the reaction process at room temperature.
Safety Information:
- (2-Chloro-3-pyridinyl)methanol is a toxic compound and contact with skin and eyes should be avoided.
-During operation or storage, care should be taken to avoid reaction with strong oxidants.
-Adequate ventilation should be provided when using or handling.
-Before use, you should understand its safety and operating procedures in detail, and comply with relevant safety operating regulations.
Nature:
-Appearance:(2-Chloro-3-pyridinyl) The methanol is a colorless or light yellow solid.
-Melting point: about 78-80°C.
-Boiling point: about 267-269°C.
-Solubility: Soluble in most organic solvents, such as ethers and alcohols.
Use:
- (2-Chloro-3-pyridinyl)methanol can be used as an important reagent in organic synthesis.
-It is commonly used in the synthesis of other pyridine compounds, such as pesticides, glyphosate, etc.
Preparation Method:
-A common synthesis method is to obtain (2-Chloro-3-pyridinyl)methanol by reacting 2-pyridinyl with hydrogen chloride. Ferrous chloride (FeCl2) is used as a catalyst in the reaction process at room temperature.
Safety Information:
- (2-Chloro-3-pyridinyl)methanol is a toxic compound and contact with skin and eyes should be avoided.
-During operation or storage, care should be taken to avoid reaction with strong oxidants.
-Adequate ventilation should be provided when using or handling.
-Before use, you should understand its safety and operating procedures in detail, and comply with relevant safety operating regulations.
Last Update：2024-04-10 22:29:15
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